An Application of Cubic Splines to Evaluate Helicity

Date: 
Tuesday, May 5, 2020 - 12:30pm
Location: 
Zoom presentation
Speaker: 
Matthew Peek
(MU Math)

This project explores different helicity functions of proteins and the convenience of Jupyter notebooks to evaluate the helicity of a protein. First, I will give an introduction of initial programming steps, such as reading in the protein files and graphing the backbone of each protein. Next, I will use a discretized helicity function to demonstrate evaluating the helices of a protein backbone and problems that may occur. Then I will give some background on cubic splines and their properties, in order to communicate their usefulness for evaluating helicity. Further, I will calculate a vector that remains invariant along helices. This, in turn, will be used to form my own helicity function.

If you wish to attend the digital presentation on Zoom, please email Matthew at mjp8r3@mail.missouri.edu to be invited.